Dental Drug Interactions
3 Contact Hours
- Drug-drug interactions
- Adverse drug reactions
- Types of drug interactions
- Dental drug interactions with the greatest potential for serious side effects
- Aspirin -oral anticoagulants (coumarins)
- Epinephrine- propranolol
- Epinephrine- tricyclic antidepressants
- Erythromycin – carbamazepine
- Erythromycin or ketoconazole- terfenadine
- Erythromycin – theophylline
- Ibuprofen – lithium
- Ibuprofen – oral anticoagulants (coumarins)
After completing this course you will be able to:
- Define a drug interaction.
- Describe the mechanism by which tetracycline and calcium interact.
- Explain the mechanism of action by which warfarin and aspirin interact to produce hemorrhage.
- Describe the mechanism of a drug interaction that involves enzyme induction, and give one example of a drug that acts in this fashion.
- List common dental drugs, interacting agents and resulting effects.
- Name four common medical drugs with which salicylates interact. For each of the drug interactions, state the potential outcome.
- Describe the type of drug with which ibuprofen may interact. State a potential outcome.
- Explain the interaction between two different CNS depressants, and state specific group of drugs that are classified as CNS depressants.
- Describe the interaction between barbiturates and oral anticoagulants and the potential outcome.
- Explain the interactions between epinephrine and B-adrenergic blocking agents and between epinephrine and tricyclic antidepressants.